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CAS 62568-57-4 Delta Sleep inducing Peptide DSIP Polypeptide Hormones 2mg/vial

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CAS 62568-57-4 Delta Sleep inducing Peptide DSIP Polypeptide Hormones 2mg/vial

China CAS 62568-57-4 Delta Sleep inducing Peptide DSIP Polypeptide Hormones 2mg/vial supplier

Large Image :  CAS 62568-57-4 Delta Sleep inducing Peptide DSIP Polypeptide Hormones 2mg/vial

Product Details:

Place of Origin: China
Brand Name: DSIP
Certification: GMP
Model Number: 62568-57-4

Payment & Shipping Terms:

Minimum Order Quantity: 1 box
Price: negotiation
Packaging Details: Original Box
Delivery Time: 5-7 business days
Payment Terms: T/T
Supply Ability: 2000 boxes/month
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Detailed Product Description

 

CAS 62568-57-4 Delta Sleep inducing Peptide DSIP Polypeptide Hormones 2mg/vial

 

Quick Detail:
 

Unit Size :2 mg/vial 
Unit Quantity :1 Vial 

Delta sleep-inducing peptide(DSIP)

Sequence:Тrр-Аlа-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Specification:  2mg/vial;
CAS#: 62568-57-4
Formula: C35H48N10O15
Molecular Weight: 848.81
Purity: 99.0%min

 

 

  Description:

 

Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
Delta sleep-inducing peptide was first discovered in 1974 by the Swiss Schoenenberger-Monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. It was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, but studies on the subject have been contradictory.

 

DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:
N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C

It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

In the brain its action may be mediated by NMDA receptors. In another study Delta sleep-inducing peptide stimulated Acetyltransferase activity through α1 receptors in rats.It is unknown where DSIP is synthesized.

 

 

Applications:

 

Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
Many roles for DSIP have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring DSIP-like immunological (DSIP-LI) response by injecting DSIP antiserum and antibodies.

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